Preserving the colonic gut flora with adsorbents, an innovative approach highlighted in Science

Preserving the colonic gut flora with adsorbents, an innovative approach highlighted in Science


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Preserving the colonic gut flora with adsorbents, an innovative approach highlighted in Science

In an article published in Science in September 2014, Ramanan Laxminarayan, Director of the Center for Disease Dynamics, Economics & Policy (CDDEP, headquarters in Washington D.C.), describes the balance there should be between two requirements to keep antibiotic effectiveness available for human health and modern medicine: (i) the conservation of the existing antimicrobial treatments and (ii) innovation to develop new drugs and new approaches to prevent and cure bacterial infections. Among the various sources of innovation currently explored (development of combination therapies, point-of-care diagnostics…), one proposed solution is the use of adsorbents to protect the gut flora during antibiotic treatments from the development of resistance phenomena.

DAV132, a product developed by Da Volterra, aims to use this strategy to protect the gut flora from the disruption caused by antibiotics. DAV132 is composed of an adsorbent which captures antibiotic residues in the late ileum and colon during antibiotic treatments. DAV132 would therefore prevent the emergence of resistant bacteria in the gut flora as well as infections by Clostridium difficile which are usually triggered by the flora disruption. You can learn more on DAV132 on this page.

Read full article: http://www.sciencemag.org/content/345/6202/1299.full