- 1
clinical trial ongoing
in patients - 4
clinical trials completed
and 2 ongoing in healthy volunteers - 495
people enrolled so far in phase 1 and phase 2
clinical trials
We are currently conducting the following clinical trials:
| Study | Phase | Title | Links |
|---|---|---|---|
| DAV132 SHIELD | Phase 2 | A European multicenter, randomized, parallel-groups study to evaluate the safety and efficacy/performance of DAV132 in hospitalized patients at high risk for Clostridium difficile infection and who receive fluoroquinolones for the treatment of acute infections | ClinicalTrials.gov |
Two additional Phase 1 studies have been launched in the USA and France, with first IND for DAV132 cleared by FDA.
Top-line results of the Phase 2 and the additional Phase 1 trials are expected by the end of the year and beginning of 2020.
The following clinical trials have been completed:
| Study | Phase | Title | Links |
|---|---|---|---|
| DAV132-CL-1001 | Phase 1 | Pharmacokinetics study using sulfasalazine (25 mg per os, pro-drug of sulfapyridine) and amoxicillin (500 mg per os) to evaluate the effect of 7.575 g enteric-coated pellets of DAV132 on the intestinal absorption of amoxicillin and sulfapyridine in healthy subjects compared with placebo effect and with the effect of 6.077 g pellets of formulated activated charcoal | Poster Article |
| DAV132-CL-1002 | Phase 1 | Safety and Efficacy Study of DAV132 in Healthy Volunteers | ClinicalTrials.gov Poster Article |
| DAV132-CL-1003 | Phase 1 | Drug-drug interaction study to characterized the influence of DAV132 on pharmacokinetic parameters of other drugs | |
| DAV132-CL-1004 | Phase 1 | Safety and Efficacy Study of Different DAV132 Dose Regimens in Healthy Volunteers | ClinicalTrials.gov Poster |
| ANTICIPATE | Observational | AssessmeNT of the Incidence of Clostridium Difficile Infections in Hospitalized Patients on Antibiotic TrEatment | ClinicalTrials.gov Poster |
