- 3
clinical trials ongoing
in patients and healthy volunteers - 6
clinical trials
completed
- 495
people enrolled so far in phase 1 and phase 2
clinical trials
We are currently conducting the following clinical trials:
| Study | Phase | Title | Links |
|---|---|---|---|
| DAV132 SHIELD | Phase 2 | A European multicenter, randomized, parallel-groups study to evaluate the safety and efficacy/performance of DAV132 in hospitalized patients at high risk for Clostridium difficile infection and who receive fluoroquinolones for the treatment of acute infections | ClinicalTrials.gov |
| DAV132-CL-1006 | Phase 1 | A French, randomized, open-label study to assess the performance of DAV132, in capturing by adsorption beta-lactams without impacting the antimicrobial efficacy, while reducing the occurrence of C. difficile colonization | |
| AXBIOME | Observational | A prospective Non-Interventional Study Assessing the Impact of Antibiotics on the Efficacy of First Line Pembrolizumab based Treatment of Metastatic Non-Small Cell Lung Carcinoma |
The following clinical trials have been completed:
| Study | Phase | Title | Links |
|---|---|---|---|
| DAV132-CL-1001 | Phase 1 | Pharmacokinetics study using sulfasalazine (25 mg per os, pro-drug of sulfapyridine) and amoxicillin (500 mg per os) to evaluate the effect of 7.575 g enteric-coated pellets of DAV132 on the intestinal absorption of amoxicillin and sulfapyridine in healthy subjects compared with placebo effect and with the effect of 6.077 g pellets of formulated activated charcoal | Poster Article |
| DAV132-CL-1002 | Phase 1 | Safety and Efficacy Study of DAV132 in Healthy Volunteers | ClinicalTrials.gov Poster Article |
| DAV132-CL-1003 DAV132-CL-1005 | Phase 1 | Drug-drug interaction study to characterized the influence of DAV132 on pharmacokinetic parameters of concomitant drugs | Press Release |
| DAV132-CL-1004 | Phase 1 | Safety and Efficacy Study of Different DAV132 Dose Regimens in Healthy Volunteers | ClinicalTrials.gov Poster |
| ANTICIPATE | Observational | AssessmeNT of the Incidence of Clostridium difficile Infections in Hospitalized Patients on Antibiotic TrEatment | ClinicalTrials.gov Poster |
