Clinical trials

CLINICAL TRIALS

Clinical trials

  • 1

    clinical trial ongoing
    in patients

  • 4

    clinical trials completed
    and 2 ongoing in healthy volunteers

  • 495

    people enrolled so far in phase 1 and phase 2
    clinical trials

We are currently conducting the following clinical trials:

StudyPhaseTitleLinks
DAV132 SHIELD Phase 2A European multicenter, randomized, parallel-groups study to evaluate the safety and efficacy/performance of DAV132 in hospitalized patients at high risk for Clostridium difficile infection and who receive fluoroquinolones for the treatment of acute infectionsClinicalTrials.gov

Two additional Phase 1 studies have been launched in the USA and France, with first IND for DAV132 cleared by FDA.
Top-line results of the Phase 2 and the additional Phase 1 trials are expected by the end of the year and beginning of 2020.

The following clinical trials have been completed:

StudyPhaseTitleLinks
DAV132-CL-1001Phase 1Pharmacokinetics study using sulfasalazine (25 mg per os, pro-drug of sulfapyridine) and amoxicillin (500 mg per os) to evaluate the effect of 7.575 g enteric-coated pellets of DAV132 on the intestinal absorption of amoxicillin and sulfapyridine in healthy subjects compared with placebo effect and with the effect of 6.077 g pellets of formulated activated charcoal Poster
Article
DAV132-CL-1002Phase 1Safety and Efficacy Study of DAV132 in Healthy VolunteersClinicalTrials.gov
Poster
Article
DAV132-CL-1003Phase 1Drug-drug interaction study to characterized the influence of DAV132 on pharmacokinetic parameters of other drugs
DAV132-CL-1004Phase 1Safety and Efficacy Study of Different DAV132 Dose Regimens in Healthy VolunteersClinicalTrials.gov
Poster
ANTICIPATEObservational AssessmeNT of the Incidence of Clostridium Difficile Infections in Hospitalized Patients on Antibiotic TrEatmentClinicalTrials.gov
Poster