Clinical trials

CLINICAL TRIALS

Clinical trials

  • 1

    clinical trial ongoing
    in patients

  • 4

    clinical trials completed
    in healthy volunteers

  • 278

    people enrolled so far in phase 1 and phase 2
    clinical trials

We are currently conducting the following clinical trials:

StudyPhaseTitleLinks
DAV132 SHIELD Phase 2A European multicenter, randomized, parallel-groups study to evaluate the safety and efficacy/performance of DAV132 in hospitalized patients at high risk for Clostridium difficile infection and who receive fluoroquinolones for the treatment of acute infectionsClinicalTrials.gov

Two additional clinical studies on DAV132 are expected to start in Q4 2018.

The following clinical trials have been completed:

StudyPhaseTitleLinks
DAV132-CL-1001Phase 1Pharmacokinetics study using sulfasalazine (25 mg per os, pro-drug of sulfapyridine) and amoxicillin (500 mg per os) to evaluate the effect of 7.575 g enteric-coated pellets of DAV132 on the intestinal absorption of amoxicillin and sulfapyridine in healthy subjects compared with placebo effect and with the effect of 6.077 g pellets of formulated activated charcoal Poster
Article
DAV132-CL-1002Phase 1Safety and Efficacy Study of DAV132 in Healthy VolunteersClinicalTrials.gov
Poster
Article
DAV132-CL-1003Phase 1Drug-drug interaction study to characterized the influence of DAV132 on pharmacokinetic parameters of other drugs
DAV132-CL-1004Phase 1Safety and Efficacy Study of Different DAV132 Dose Regimens in Healthy VolunteersClinicalTrials.gov
Poster
ANTICIPATEObservational AssessmeNT of the Incidence of Clostridium Difficile Infections in Hospitalized Patients on Antibiotic TrEatmentClinicalTrials.gov
Poster